HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxybenzenesulfonic acid → HCID 86630643, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxybenzenesulfonic acid | HCID 15619088 | — |
| Reactant | Tak-593 | HCID 24767976 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86630643 | HCID 86630643 | 75% |
Reaction Steps
Using N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (2.00 g, 4.49 mmol), ethanol (100 mL) and benzenesulfonic acid monohydrate (0.83 g, 4.71 mmol), and in the same manner as in Example 152, the title compound (2.02 g, 75%) was obtained as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273741B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-802f911a50ec42f6b4655f947a532012 |
| Source note | uspto-grants-2012_09 |