HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonic Acid → HCID 86630644, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonic Acid | HCID 6395 | — |
| Reactant | Tak-593 | HCID 24767976 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86630644 | HCID 86630644 | 67% |
Reaction Steps
Using N-[5-({2-[(cyclopropylcarbonyl)amino]imidazo[1,2-b]pyridazin-6-yl}oxy)-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide (2.00 g, 4.49 mmol), ethanol (80 mL) and methanesulfonic acid (0.34 mL, 4.71 mmol), and in the same manner as in Example 152, the title compound (1.63 g, 67%) was obtained as white crystals.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273741B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e528889db04441dda7076921bea40549 |
| Source note | uspto-grants-2012_09 |