Triacetoxyperiodinane → HCID 64997388, compound

Participants

Reaction Conditions

Reaction Steps

154 g N-(2-hydroxy-propyl)-isonicotinamide in 500 mL dichlormethane was added to a solution of Dess-Martin reagenz in 1.5 L dichlormethane at 0° C. under nitrogen. The reaction was stirred for 30 min. at 0° C. and 4 h at RT. The mixture was concentrated and the crude product was purified by chromatographie on silica to give 91 g of the desired product.

Provenance & Evidence