HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-2-butenoyl chloride → HCID 57505585, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-2-butenoyl chloride | HCID 102394 | — |
| Reactant | N-[6-(3-amino-4-methylphenoxy)imidazo[1,2-b]pyridazin-2-yl]cyclopropanecarboxamide | HCID 57505476 | — |
| Solvent | Dimethylacetamide | HCID 31374 | — |
| Product | HCID 57505585 | HCID 57505585 | 57% |
Reaction Steps
Using N-[6-(3-amino-4-methylphenoxy)imidazo[1,2-b]pyridazin-2-yl]cyclopropanecarboxamide (200 mg, 0.62 mmol), N,N-dimethylacetamide (2.0 mL) and 3,3-dimethylacryloyl chloride (83 μL, 0.74 mmol), and in the same manner as in Example 120, the title compound (142 mg, 57%) was obtained as a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273741B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-a02854b8b4ac4acbada93d4817f328c1 |
| Source note | uspto-grants-2012_09 |