HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86686043, compound → HCID 82414136, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86686043 | HCID 86686043 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 82414136 | HCID 82414136 | 91.8% |
Reaction Steps
25 g 1-benzyl-4-(5-methyl-oxazol-2-yl)-1,2,3,6-tetrahydro-pyridine and 6 g palladium charcoal in 200 mL tetrahydrofuran and 200 mL ethanol were stirred at RT for 12 h under hydrogen atmosphere (30 psi). The mixture was filtered and the filtrate concentrated to yield 15 g of the desired product. Rf: 0.05 (petrolether/ethyl acetate=1/1), (M+H)+: 167
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08642774B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-d51b713c2cb240d5a766bad5c6e20493 |
| Source note | uspto-grants-2014_02 |