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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391385Generated: October 30, 2026

Potassium Carbonate → HCID 57505623, compound

https://huagongshe.com/reaction/2391385

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantN-(6-iodoimidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamideHCID 57386058—
ReactantHCID 57505437HCID 57505437—
SolventDimethylformamideHCID 6228—
ProductHCID 57505623HCID 5750562361.3%

Reaction Steps

In the same manner as in Example 257 and using N-(6-iodoimidazo[1,2-b]pyridazin-2-yl)cyclopropanecarboxamide (210 mg, 0.65 mmol), 4-chloro-3-{[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]amino}phenol (240 mg, 0.97 mmol), potassium carbonate (220 mg, 1.6 mmol) and N,N-dimethylformamide (1.5 mL) as starting materials, the title compound (180 mg, 61%) was obtained as a brown solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273741B2
Source datasetuspto-grants-2012_09
ORD IDord-1367d020ce3f41a981926fc04aff5f80
Source noteuspto-grants-2012_09