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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391569Generated: October 30, 2026

Ammonia → HCID 25152657, compound

https://huagongshe.com/reaction/2391569

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniaHCID 222—
ReactantHCID 68767604HCID 68767604—
SolventMethanolHCID 887—
ProductHCID 25152657HCID 25152657—

Reaction Steps

In a similar manner as described for example 1, 195 mg of methyl 5-(1H-imidazo[4,5-c]pyridin-1-yl)-3-{[2-(trifluoromethyl)benzyl]oxy}thiophene-2-carboxylate (compound B1a) and 36 ml of a saturated solution of ammonia in methanol yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273890B2
Source datasetuspto-grants-2012_09
ORD IDord-ca245fe6a7214545b6d8228a19ef1920
Source noteuspto-grants-2012_09