Thioacetamide → HCID 86686066, compound

Participants

Reaction Steps

A mixture of 33 g 5-bromo-7-methyl-azepan-4-one hydrobromide and 3-bromo-7-methyl-azepan-4-one hydrobromide and 8.6 g thioacetamide in 400 mL dry EtOH was refluxed overnight. The reaction mixture was concentrated to give 30 g of the desired product, which was used for the next step without further purification. Rf: 0.2 (DCM/MeOH=20/1), (M+H)+=183

Provenance & Evidence