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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391698Generated: October 30, 2026

Potassium Carbonate → HCID 68764920, compound

https://huagongshe.com/reaction/2391698

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant1-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 123062—
Reactantmethyl 3-hydroxy-5-(1H-imidazo[4,5-c]pyridin-1-yl)thiophene-2-carboxylateHCID 68766294—
SolventDimethylformamideHCID 6228—
ProductHCID 68764920HCID 68764920—

Reaction Steps

In a similar manner as described for example B14, 102.8 mg of 4-(trifluoromethyl)benzyl bromide, 100 mg of methyl 3-hydroxy-5-(1H-imidazo[4,5-c]pyridin-1-yl)thiophene-2-carboxylate, 59.7 mg of potassium carbonate in 3 ml anhydrous DMF yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08273890B2
Source datasetuspto-grants-2012_09
ORD IDord-177cc6c7f6fd46469e6bb7b8d851b4d7
Source noteuspto-grants-2012_09