HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2391751Generated: October 31, 2026
Thionyl Chloride → 4-Bromo-2-chlorobenzoyl chloride
https://huagongshe.com/reaction/2391751
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 4-Bromo-2-chlorobenzoic acid | HCID 108829 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Bromo-2-chlorobenzoyl chloride | HCID 15592207 | — |
Reaction Steps
To a mixture of 15 g of 4-bromo-2-chlorobenzoic acid in 25 ml DMF is added 10 ml thionyl chloride at room temperature and the reaction mixture is stirred for 16 h at 75° C. Excess of thionyl chloride is removed under reduced pressure to give 4-bromo-2-chlorobenzoyl chloride as crude material that is used for the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08273890B2 |
|---|
| Source dataset | uspto-grants-2012_09 |
|---|
| ORD ID | ord-894b1c2af8fc4a8892f194a3d8c40702 |
|---|
| Source note | uspto-grants-2012_09 |
|---|
