HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[2-(Dimethylamino)ethoxy]aniline → 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[2-(Dimethylamino)ethoxy]aniline | HCID 6484655 | — |
| Reactant | 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [3-(4-ethyl-piperazin-1-yl)phenyl]-amide | HCID 44515669 | — |
| Product | 8-Isoquinolin-4-yl-quinoxaline-5-carboxylic acid [4-(2-dimethylamino-ethoxy)-phenyl]-amide | HCID 44515670 | — |
Reaction Steps
The title compound was prepared in analogy to the procedure described in Step 14.1 but using 4-(2-dimethylamino-ethoxy)-phenylamine (Step 5.1) and 8-isoquinolin-4-yl-quinoxaline-5-carboxylic acid (Example 52). Title compound: ESI-MS: 464.1 [M+H]+; tR=8.23 min (System 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273882B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-f0f1ffbc2dc144dca9ab57fd83c8f2b7 |
| Source note | uspto-grants-2012_09 |