HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine hydrochloride → HCID 44512873, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine hydrochloride | HCID 66914536 | — |
| Reactant | 8-(3-Methoxy-2,5-dimethyl-phenyl)quinoxaline-5-carboxylic acid | HCID 66914589 | — |
| Product | HCID 44512873 | HCID 44512873 | — |
Reaction Steps
The title compound was prepared in analogy to the procedure described in Step 14.1 but using 8-(3-methoxy-2,5-dimethyl-phenyl)-quinoxaline-5-carboxylic acid (Step 97.1), 5-(4-ethyl-piperazin-1-ylmethyl)-pyridin-2-ylamine hydrochloride (Step 26.1) and stirring the reaction mixture for 24 h at rt. The crude product was purified by silica gel column chromatography (DCM/MeOH/NH3aq, 94:5:1). Title compound: ESI-MS: 511.1 [M+H]+; tR=3.75 min (System 1); TLC: Rf=0.29 (DCM/MeOH/NH3aq, 94:5:1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08273882B2 |
| Source dataset | uspto-grants-2012_09 |
| ORD ID | ord-e59290370a754e5f82adfa32c7e78984 |
| Source note | uspto-grants-2012_09 |