関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-(2-Phenylethyl)oxirane | HCID 135955 | — |
| 反応物 | Ammonia methanol | HCID 21705897 | — |
| 生成物 | 1-Amino-4-phenylbutan-2-ol | HCID 15760987 | — |
反応手順
2-(2-phenylethyl)oxirane (8.0 g, 54 mmol) was placed in a sealed tube with 7N NH3-MeOH (130 mL) and stirred 2 hours at 70° C. followed by concentration to a clear oil (and was used without further purification in the following step.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08273782B2 |
|---|
| 出典データセット | uspto-grants-2012_09 |
|---|
| ORD ID | ord-2fafa5b6418f48e9972a2ce2156309a0 |
|---|
| 出典メモ | uspto-grants-2012_09 |
|---|
