1-(tert-Butoxycarbonyl)-4-methylenepyrrolidine-2-carboxylic acid → (1-{2-[5-(4-Bromo-phenyl)-1H-imidazol-2-yl]-4-methylene-pyrrolidine-1-carbonyl]-2-methyl-propyl)-carbamic acid methyl ester

Participants

Role	Name	HCID	Charge
Reactant	1-(tert-Butoxycarbonyl)-4-methylenepyrrolidine-2-carboxylic acid	HCID 21762564	—
Reactant	Methyl (1-(2-(4-(4-bromophenyl)-1H-imidazol-2-YL)pyrrolidin-1-YL)-3-methyl-1-oxobutan-2-YL)carbamate	HCID 66620141	—
Product	(1-{2-[5-(4-Bromo-phenyl)-1H-imidazol-2-yl]-4-methylene-pyrrolidine-1-carbonyl]-2-methyl-propyl)-carbamic acid methyl ester	HCID 66621522	—

Reaction Steps

This compound was prepared using the procedure used to prepare (1-{2-[5-(4-Bromo-phenyl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester using 4-Methylene-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08273341B2
Source dataset	uspto-grants-2012_09
ORD ID	ord-48463ae673b74685ba01063c0f51a921
Source note	uspto-grants-2012_09