Dimethyl acetylenedicarboxylate → HCID 21860268, compound

HRID 2392526Notes

Reaction equation

HRID 2392526 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:5]=[C:4]([C:13]2[CH:18]=[CH:17][C:16]([N:19]([CH3:21])[CH3:20])=[CH:15][CH:14]=2)[C:3]=1[C:22]#[N:23].[C:24]([C:30]([O:32][CH3:33])=[O:31])#[C:25][C:26]([O:28][CH3:29])=[O:27]>>[NH2:23][C:22]1[C:25]([C:26]([O:28][CH3:29])=[O:27])=[C:24]([C:30]([O:32][CH3:33])=[O:31])[N:1]=[C:2]2[N:6]([C:7]3[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=3)[N:5]=[C:4]([C:13]3[CH:18]=[CH:17][C:16]([N:19]([CH3:20])[CH3:21])=[CH:15][CH:14]=3)[C:3]=12

Participants

3

Reactant 2

HCID 12980Dimethyl acetylenedicarboxylateHCID 915880HCID 915880, compound

Product 1

HCID 21860268HCID 21860268, compound

Procedure

Using 1.57 mg (5 mmol) of 5-amino-3-(p-dimethylaminophenyl)-1-phenylpyrazole-4-carbonitrile [see Chem. Ber., 99, 3492 (1966)] and 0.85 g (6 mmol) of dimethyl acetylenedicarboxylate, the entitled product having a melting point of 207° to 208° C. was obtained in the same manner as in Example 2-(2).

Workup

  1. customwas obtained in the same manner as in Example 2-(2)

Sources & evidence

ORD record
ord-94274b3f01f74f02b135d48b6f7dadf8
Source dataset
uspto-grants-1998_09
Patent number
US05801008

Reaction notes

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