Methanol → HCID 18979818, compound

Participants

Reaction Steps

A solution of 3-(4-chloro-2-nitrobenzoyl)-bicyclo[3,2,1]-octane-2,4-dione (2.54 mmol) and 2 drops of conc. sulfuric acid in 20 ml of methanol is heated under reflux for 48 hours. The reaction mixture is concentrated and the residue is taken up in ether. The ethereal solution is washed with aqueous sodium bicarbonate and with brine, dried and evaporated to dryness to give 2-methoxy-3-(4-chloro-2-nitrobenzoyl)bicyclo-[3,2,1]-octane-4-one.

Provenance & Evidence