Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Potassium Carbonate → 4'-(8-Hydroxyoctyloxy)biphenyl-4-carbonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | 1-Octanol, 8-chloro- | HCID 90012 | — |
| 반응물 | 4'-Hydroxy-4-biphenylcarbonitrile | HCID 140610 | — |
| 용매 | Methyl Ethyl Ketone | HCID 6569 | — |
| 생성물 | 4'-(8-Hydroxyoctyloxy)biphenyl-4-carbonitrile | HCID 15048406 | 59.2% |
반응 단계
A solution of 5.0 g of 4'-hydroxybiphenyl-4-carbonitrile and 5.1 g of 8-chloro-1-octanol in 100 ml of ethyl methyl ketone was treated with 14.1 g of finely powdered potassium carbonate and the mixture was heated under slight reflux overnight. The suspension was suction filtered and the filtrate was concentrated in a vacuum. Chromatography of the residue on silica gel with hexane/ethyl acetate (vol. 1:1) gave 4.9 g of 4'-(8-hydroxyoctyloxy)biphenyl-4-carbonitrile.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05800733 |
| 출처 데이터셋 | uspto-grants-1998_09 |
| ORD ID | ord-58fbab453721434b96adce0769141d78 |
| 출처 메모 | uspto-grants-1998_09 |