2-Methoxy-5-nitrophenol → 3-(2-Diisopropylaminoethoxy)-4-methoxyaniline
Reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[OH:12].Cl.[CH:14]([N:17]([CH:21]([CH3:23])[CH3:22])[CH2:18][CH2:19]Cl)([CH3:16])[CH3:15]>>[CH:14]([N:17]([CH:21]([CH3:23])[CH3:22])[CH2:18][CH2:19][O:12][C:4]1[CH:5]=[C:6]([CH:7]=[CH:8][C:3]=1[O:2][CH3:1])[NH2:9])([CH3:16])[CH3:15]Participants
3
Procedure
The title compound was prepared from 2-methoxy-5-nitrophenol and 2-diisopropylaminoethyl chloride hydrochloride, following a procedure similar to that described in Descriptions 1 and 2 (81%).
Sources & evidence
- ORD record
- ord-cda4f54384c44a709688d3f651b027c8
- Source dataset
- uspto-grants-1998_09
- Patent number
- US05801170
Reaction notes
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