2-Methoxy-5-nitrophenol → 4-Methoxy-3-[2-(morpholin-4-yl)ethoxy]aniline

HRID 2392630Notes

Reaction equation

HRID 2392630 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N+:9]([O-])=O)=[CH:5][C:4]=1[OH:12].Cl.Cl[CH2:15][CH2:16][N:17]1[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1>>[N:17]1([CH2:16][CH2:15][O:12][C:4]2[CH:5]=[C:6]([CH:7]=[CH:8][C:3]=2[O:2][CH3:1])[NH2:9])[CH2:22][CH2:21][O:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 694712-Methoxy-5-nitrophenolHCID 77210Morpholine, 4-(2-chloroethyl)-, hydrochloride (1:1)

Product 1

HCID 186726704-Methoxy-3-[2-(morpholin-4-yl)ethoxy]aniline

Procedure

The title compound was prepared from 2-methoxy-5-nitrophenol and 4-(2-chloroethyl)morpholine hydrochloride using a similar procedure to Descriptions 1 and 2 (63%).

Sources & evidence

ORD record
ord-0980829a754649e794bf4924a40f0397
Source dataset
uspto-grants-1998_09
Patent number
US05801170

Reaction notes

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