2'-Methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxylic acid → 4-methoxy-3-[2-(1-pyrrolidinyl)ethoxy]Benzenamine

HRID 2392640Notes

Reaction equation

HRID 2392640 reaction equation
[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:14]=[C:13]([N+:15]([O-])=O)[CH:12]=[CH:11][C:10]=2[O:18][CH3:19])[CH2:5][CH2:4][CH2:3][CH2:2]1.CC1C=C(C2OC(C)=NN=2)C=CC=1C1C=CC(C(O)=O)=CC=1>>[N:1]1([CH2:6][CH2:7][O:8][C:9]2[CH:14]=[C:13]([CH:12]=[CH:11][C:10]=2[O:18][CH3:19])[NH2:15])[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 186900662'-Methyl-4'-(5-methyl-1,3,4-oxadiazol-2-yl)biphenyl-4-carboxylic acidHCID 189800932-(2-Pyrrolidin-1-ylethoxy)-4-nitroanisole

Product 1

HCID 189801284-methoxy-3-[2-(1-pyrrolidinyl)ethoxy]Benzenamine

Procedure

The title compound was prepared from 2-(2-pyrrolidin-1-ylethoxy)-4-nitroanisole (D30) using a similar procedure to Description 2 (96%).

Sources & evidence

ORD record
ord-b7f64e46616847de99227af3217ab28f
Source dataset
uspto-grants-1998_09
Patent number
US05801170

Reaction notes

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