Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2392682Generated: October 30, 2026

4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic Acid → N-[3-(2-Dimethylaminopropoxy)-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamide

https://huagongshe.com/reaction/2392682

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzoic AcidHCID 11130168—
Reactant3-(2-Dimethylaminopropoxy)-4-methoxyanilineHCID 18980147—
ProductN-[3-(2-Dimethylaminopropoxy)-4-methoxyphenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxamideHCID 18980083—

Reaction Steps

The title compound was prepared from 2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-carboxylic acid (EP 0533268 A1) and 3-(2-dimethylaminopropoxy)-4-methoxyaniline (D7) using a similar procedure to Example 1 (34%) mp 105°-110° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05801170
Source datasetuspto-grants-1998_09
ORD IDord-cdfd9749ce474b078b1f79f6f96ba87f
Source noteuspto-grants-1998_09