HCID 18980084, compound → HCID 18980125, compound

HRID 2392695Notes

Reaction equation

HRID 2392695 reaction equation
[CH3:1][N:2]([CH3:25])[CH2:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]([NH:14][C:15](=[O:24])[C:16]2[CH:21]=[CH:20][C:19](Br)=[C:18]([CH3:23])[CH:17]=2)[CH:9]=[CH:10][C:11]=1[O:12][CH3:13].[N:26]1[CH:31]=[CH:30][CH:29]=[CH:28][C:27]=1[C:32]1[CH:37]=[CH:36][C:35](B(O)O)=[CH:34][CH:33]=1>>[CH3:1][N:2]([CH3:25])[CH2:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]([NH:14][C:15]([C:16]2[CH:21]=[CH:20][C:19]([C:35]3[CH:34]=[CH:33][C:32]([C:27]4[CH:28]=[CH:29][CH:30]=[CH:31][N:26]=4)=[CH:37][CH:36]=3)=[C:18]([CH3:23])[CH:17]=2)=[O:24])[CH:9]=[CH:10][C:11]=1[O:12][CH3:13]

Participants

3

Reactant 2

HCID 18980084HCID 18980084, compoundHCID 18980112B-(4-(2-Pyridinyl)phenyl)boronic acid

Product 1

HCID 18980125HCID 18980125, compound

Procedure

The title compound was prepared from N-[3-(2-dimethylaminoethoxy)-4-methoxyphenyl)-4-bromo-3-methylbenzamide (163 mg) and 4-(2-pyridyl)phenylboronic acid (D77, 154 mg) using the same procedure as in Description 15 and isolated as a white solid (171 mg, 89%). Mp 149°-151° C.

Sources & evidence

ORD record
ord-59e98b6380fb407da7b3a3d67a7574a8
Source dataset
uspto-grants-1998_09
Patent number
US05801170

Reaction notes

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