HuagongsheHuagongshe Chemistry Print Report · For research reference only
benzyl (2S)-2-aminopropanoate → N-[3-acetylthio-2-(1-indanyl)-1-oxopropyl)alanine benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | benzyl (2S)-2-aminopropanoate | HCID 726858 | — |
| Reactant | 3-Acetylthio-2-(1-indanyl)propanoic acid | HCID 18793868 | — |
| Product | N-[3-acetylthio-2-(1-indanyl)-1-oxopropyl)alanine benzyl ester | HCID 53659209 | 72% |
Reaction Steps
Using the procedure described in Example 60, but starting with 3-acetylthio-2-(1-indanyl)propanoic acid and alanine benzyl ester, N-[3-acetylthio-2-(1-indanyl)-1-oxopropyl]alanine benzyl ester is obtained in a 72% yield in the form of a white solid, having the following characteristics: m.p.: 95° C.; Rf =0.17 [cyclohexane/ethyl acetate (4:1 by volume)].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05801274 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-a6e48488bc3a4c4f8e6fb36c38e12b89 |
| Source note | uspto-grants-1998_09 |