Hydrochloric Acid → 3,3'-Dichlorobenzidine

Participants

Reaction Steps

Separately, after a press cake of 3,3'-dichlorobenzidine hydrochloride in an amount corresponding to 150 parts of the 3,31 -dichlorobenzidine expressed by following Formula (1) was blended with 186 parts of 35% hydrochloric acid, 1500 parts of water and 750 parts of ice, an aqueous solution of 86 parts of sodium nitrite was added under exposure to ice to obtain a tetrazo solution of 3,3'-dichlorobenzidine. 16.4 parts of the 4-acetoacetylamino acetoacetylamino benzamide expressed by the following Formula (3): ##STR7## were added to this 3,3'-dichlorobenzidine tetrazo solution, then the result was mixed for three hours to obtain a reaction intermediate (B1).

Provenance & Evidence