Acrylonitrile → HCID 18978058, compound

Participants

Reaction Conditions

Reaction Steps

530 mg of acrylonitrile were slowly added to 1.88 g of N-(tert-butoxycarbonyl)-N,N'-dimethyl-ethylenediamine, while cooling with ice. The mixture was stirred at 0° C. for 1 hour, at RT for 14 hours and at 60° C. for 2 hours. The volatile constituents were removed in vacuo and the residue was purified by chromatography over silica gel (EA:MeOH 9:1). 1.92 g of product were obtained. MS(Cl): 242 (M+H)⊕, 186, 142

Provenance & Evidence