HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl orthoformate → HCID 54487700, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl orthoformate | HCID 31214 | — |
| Reactant | 1-[4-Chloro-2-(methanesulfonyl)phenyl]-3-cyclopropylpropane-1,3-dione | HCID 54551365 | — |
| Solvent | Acetic Anhydride | HCID 7918 | — |
| Product | HCID 54487700 | HCID 54487700 | 99.7% |
Reaction Steps
A mixture of 1-[4-chloro-2-(methylsulphonyl)phenyl]-3-cyclopropylpropan-1,3-dione (7.1 g) and triethyl orthoformate (6.9 g) in acetic anhydride was stirred and heated at reflux for 2 hours. The mixture was evaporated to dryness, toluene was added and the solution was re-evaporated to give 1-[4-chloro-2-(methylsulphonyl)phenyl]-3-cyclopropyl-2-ethoxymethylenepropan-1,3-dione (8.4 g) as a red gum which was not purified further.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05804532 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-d72a8b7d445542fb8ac9f30a09198a80 |
| Source note | uspto-grants-1998_09 |