Ethylenediamine → HCID 86184604, compound

HRID 2393078Notes

Reaction equation

HRID 2393078 reaction equation
[CH2:1]([NH2:4])[CH2:2][NH2:3].[C:5]([C:7]1[C:16]2[C:11](=[C:12]([CH3:21])[CH:13]=[C:14]([N:18]=[C:19]=[S:20])[C:15]=2[CH3:17])[N:10]=[CH:9][CH:8]=1)#[N:6]>C1(C)C=CC=CC=1>[NH2:3][CH2:2][CH2:1][NH:4][C:19](=[S:20])[NH:18][C:14]1[C:15]([CH3:17])=[C:16]2[C:11](=[C:12]([CH3:21])[CH:13]=1)[N:10]=[CH:9][CH:8]=[C:7]2[C:5]#[N:6]

Participants

4

Reactant 2

HCID 3301EthylenediamineHCID 18979047HCID 18979047, compound

Product 1

HCID 86184604HCID 86184604, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

To a solution of ethylenediamine (2.93 mL) in toluene (30 mL) is slowly added a solution of 4-cyano-5,8-dimethyl-6-isothiocyanatoquinoline (2.1 g, 8.78 mmol) in toluene (100 mL). The reaction mixture is stirred at room temperature overnight. The solid which forms is filtered, washed well with toluene, and dried to afford 6-[N'-(2-aminoethyl)thioureido]-4-cyano-5,8-dimethylquinoline.

Workup

  1. filtrationThe solid which forms is filtered
  2. washwashed well with toluene
  3. customdried

Sources & evidence

ORD record
ord-d5e8107d079b4a01b91b9c5d7cd95970
Source dataset
uspto-grants-1998_09
Patent number
US05804587

Reaction notes

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