Dichloromethane → HCID 131720816, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of 8-methoxyquinoline-5-carboxylic acid (1.5 g) in dichloromethane (12 ml) was cooled to 0° C. and treated with oxalyl chloride (1.3 ml) followed by DMF (8 drops). The reaction was allowed to warm to room temperature and stirred overnight. The solvent was removed in vacuo and the residue azeotroped with toluene (2×10 ml) to yield the desired product (1.61 g) as an off-white powder.

Provenance & Evidence