2-Naphthol → HCID 18979198, compound

Participants

Reaction Steps

2-Naphthol (1.152 g) and ethyl 7-hydroxy-7-phenyl-heptanoate (2g) were dissolved in methylene chloride (20 ml) followed by dropwise addition of boron trifluoride-ether complex (0.56 g). After 5 hours of stirring, the reaction mixture was extracted with chloroform and the extract was washed with water, dried, and concentrated. The residue was applied to a silica gel column (hexane-ethyl acetate) to provide the title compound (1.94 g).

Provenance & Evidence