Ethyl isocyanate → HCID 18979206, compound

Participants

Reaction Steps

To a solution of 6-(4-methoxyphenyl)-6-(3-methyl-1,4-naphthoquinon-2-yl)hexanohydroxamic acid (0.5 g) in THF was added a THF (2 ml) solution of ethyl isocyanate (0.1 g) at room temperature and the mixture was stirred for 2 hours. The solvent was then distilled off under reduced pressure and the residue was purified by silica gel column chromatography (hexane-ethyl acetate=1:1). The resulting oil was crystallized from hexane to provide the title compound (0.29 g).

Provenance & Evidence