反应详情

Methyl 2-chloro-4-methanesulfonyl-3-dimethoxymethylbenzoate in an amount of 3.0 g (9.3 mmol) was dissolved in methanol in a volume of 30 ml, and to the resulting solution, was added 10% aqueous solution of sodium hydroxide in a volume of 20 ml, and then, the mixture was stirred for 1 hour at an ambient temperature. The reacted-mixture was then added with 1-N hydrochloric acid to make it acidic, and crystals precipitated were filtrated, washed with water and dried to obtain the objective compound in an amount of 2.5 g.

1. customcrystals precipitated
2. filtrationwere filtrated
3. washwashed with water
4. customdried
5. customto obtain the objective compound in an amount of 2.5 g