Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Lithium Hydroxide | HCID 3939 | — |
| Reactant | HCID 10488027 | HCID 10488027 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 15406934 | HCID 15406934 | 100% |
Reaction Steps
Ethyl α,α-dimethyl-3-pyridylacetate (disclosed in EP Application 0 288 279, published Oct. 26, 1988) (2.67 grams, 13.8 mmoles) was dissolved in EtOH (11.1 ml.) and a 1.0M LiOH in water (33.3 ml.) (33.4 mmoles) was added. The mixture was stirred at 25° C. for 4 hours. 1N HCl (38.73 ml.) was added and after 5 minutes the mixture was evaporated to dryness to give the titlle compound (Yield: 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05807853 |
|---|
| Source dataset | uspto-grants-1998_09 |
|---|
| ORD ID | ord-e7b3278d49fc46a690642d4d31ac413a |
|---|
| Source note | uspto-grants-1998_09 |
|---|
