HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylamide → Phenidone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylamide | HCID 6579 | — |
| Reactant | Phenylhydrazine | HCID 7516 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Catalyst | Tetrabutylammonium Bromide | HCID 74236 | — |
| Product | Phenidone | HCID 7090 | — |
Reaction Steps
Phenylhydrazine (10.8 g, 0.1 mol), and acrylamide (7.8 g, 0.11 mol), pulverized potassium hydroxide (12.5 g, 0.22) and a catalytic amount of tetrabutylammonium bromide is refluxed for 30 minutes. The precipitate is filtered and washed with toluene. The crystalline sold is dissolved in water. Acidification with acetic acid, filtration and drying gives 1-phenyl-3-pyrazolidone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05807863 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-a82caac1fad34dcb8cdc22597bbf516d |
| Source note | uspto-grants-1998_09 |