Methanol → HCID 9906742, compound

Participants

Reaction Steps

The process is performed as in Example 3 but starting with 6.9 g of 10-(3-carboxybenzylidene)-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one, 50 ml of methanol, 250 ml of dimethylformamide and 0.7 g of 10% palladium-on-charcoal. After evaporation of the solvents and trituration of the solid obtained with 100 ml of methanol, 5.1 g of 10-(3-carboxybenzyl)-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one are obtained in the form of an off-white solid melting above 260° C., which product is converted into the sodium salt of formula C21 H14N3O3Na (Analysis, % calculated C 66.49, H: 3.72, N: 11.08, O: 12.65, Na : 6.06, % found C: 66.6, H: 3.7, N: 10.9).

Provenance & Evidence