Sodium Carbonate → HCID 57031619, compound

Participants

Reaction Steps

To 0.5 g of 10-(3-nitrobenzylidene)-5H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one suspended in 15 ml of absolute ethanol are added 1.57 g of tin chloride dihydrate. The reaction medium is refluxed for 6 hours and then left at a temperature in the region of 20° C. for 72 hours. The reaction medium is treated with 30 ml of saturated sodium carbonate solution and the insoluble material is filtered off, washed with water, dried and then taken up in 80 ml of dimethylformamide. The new insoluble material is filtered off and discarded. The filtrate is concentrated to dryness under reduced pressure and dried (5 mmHg; 0.65 kPa) at 55° C. 0.28 g of 10-(3-aminobenzylidene)-5H-imidazo-[1,2-a]indeno[1,2-e]pyrazin-4-one is thus obtained in the- form of an orange-coloured powder, the melting point of which is greater than 260° C. (Analysis, C20H14 N4O.0.39 H2O.0.48 DMF; % calculated C: 73.61; H: 4.32; N: 17.17; % found C: 73.6; H: 3.9; N: 16.9).

Provenance & Evidence