HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-(1-Chloroethyl)-9H-fluorene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 20371-86-2 | HCID 265845 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-(1-Chloroethyl)-9H-fluorene | HCID 14572484 | — |
Reaction Steps
Thionyl chloride (1.1 ml) and catalytically effective amount of N,N-dimethylformamide were added to a solution of 2-(1-hydroxyethyl)-9H-fluorene (1.05 g) in methylene chloride (15 ml) under ice-cooling, and the mixture was stirred at room temperature for 30 minutes and then heated under reflux for 1 hour. By evaporating the solvent under reduced pressure, 2-(1-chloroethyl)-9H-fluorene was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05807880 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-07ed4ea18b1a4fd9b1ae585a97fa8fbf |
| Source note | uspto-grants-1998_09 |