Boron tribromide → HCID 15407850, compound

Participants

Reaction Steps

Under an inert atmosphere, 0.1 ml of boron tribromide is added dropwise to 90 mg of 6-hydroxy-10-methoxy-7,12-dioxabenz[a]anthracene in solution in 3 ml of dichloromethane at 0° C. After 4 hours, the mixture is hydrolyzed. The organic phase is dried over magnesium sulfate and concentrated under vacuum. The bis-hydroxylated compound is purified by flash chromatography on silica gel (eluent: petroleum ether/ethyl acetate).

Provenance & Evidence