2,3-Dichloro-5,6-dicyano-1,4-benzoquinone → HCID 18976134, compound

Participants

Reaction Steps

Under an inert atmosphere, 370 mg of methyl 1,2,3,4,4a,6a-hexahydro-7,12-dioxabenz[a]anthracene-5-carboxylate in solution in 10 ml of toluene are brought to reflux for 6 hours in the presence of 986 mg of DDQ. After cooling, the reaction mixture is washed with 8% sodium hydroxide solution. The organic phase is dried over magnesium sulfate and then concentrated under vacuum. Purification is performed by chromatography on silica gel (eluent: petroleum ether/ethyl acetate, 95:5).

Provenance & Evidence