HCID 18691585, compound → 4,6-Difluoro-5-methylbenzo[b]thiophene

HRID 2393527Notes

Reaction equation

HRID 2393527 reaction equation
C(O[CH:4](OCC)[CH2:5][S:6][C:7]1[CH:12]=[C:11]([F:13])[C:10]([CH3:14])=[C:9]([F:15])[CH:8]=1)C.C(OC(OCC)CSC1C=CC(C)=C(F)C=1)C>>[F:13][C:11]1[C:12]2[CH:4]=[CH:5][S:6][C:7]=2[CH:8]=[C:9]([F:15])[C:10]=1[CH3:14]

Participants

3

Reactant 2

HCID 18691585HCID 18691585, compoundHCID 18691589HCID 18691589, compound

Product 1

HCID 186915814,6-Difluoro-5-methylbenzo[b]thiophene

Procedure

The same procedure as in Reference Example 1 (3) is repeated, except that 1,1-diethoxy-2-(3,5-difluoro4-methylphenylthio)ethane is substituted for the 1,1-diethoxy-2-(3-fluoro-4-methylphenylthio)ethane, to obtain 4,6-difluoro-5-methylbenzo[b]thiophene.

Sources & evidence

ORD record
ord-366d85851b0349988c89c62f4d936668
Source dataset
uspto-grants-1998_09
Patent number
US05807887

Reaction notes

Loading…