HCID 86753100, compound → HCID 86753099, compound

Participants

Reaction Steps

To a stirred solution of 2-(7-nitro-(1,2,3,4-tetrahydronaphthyl))-N (phenylmethyl)trifluoroacetamide (2.55 g, 6.75 mmol) in THF/MeOH (100 ml, 1:1) was added a catalytic amount of 10% Pd/C. The mixture was hydrogenated at 50 psi for 1 hr, filtered through celite, and concentrated to give 2-(7-amino-(1,2,3,4-tetrahydronaphthyl))-N-(phenylmethyl) trifluoroacetamide which was homogeneous by TLC and used immediately in the next step.

Provenance & Evidence