Acrylonitrile → HCID 18976536, compound

Participants

Reaction Steps

87.0 g (0.762 mol) of 1-methylhydantoin and 48.55 g (0.915 mol) of acrylonitrile are introduced into an apparatus at an internal temperature of 67° C., and 8 ml of 1 molar sodium hydroxide solution are added dropwise over the course of 12 minutes, during which an exothermic reaction occurs and the temperature rises to 75° C. The reaction mixture is then stirred for 1 hour and 48 minutes at 75° C.-103° C. and then neutralized with 0.92 g of 32% hydrochloric acid. The reaction product is purified by vacuum distillation, giving 94.7 g (74.3% of theory) of crystalline 3-(3-methyl-2,4-dioxoimidazolidin-1-yl)propionitrile, whose melting point is 53° C.

Provenance & Evidence