HRID2393855

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCOC(=O)c1ccc(C#Cc2ccc3c(c2)C(C)(C)CC=C3C(C)(C)C)cc1

HCID18314563

未命名化合物

2 次

结构：CC1(C)CC=C(c2ccccc2)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21

HCID18314590

未命名化合物

2 次

PRODUCTS

生成物

结构：CC(C)(C)C1=CCC(C)(C)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21

HCID18314592

未命名化合物

PROCEDURE

实验过程

Employing the same general procedure as for the preparation of 4-[(7,8-dihydro-8,8-dimethyl-5-phenylnaphth-2-yl)ethynyl]benzoic acid (Compound 97), 51 mg (0.13 mmol) of ethyl 4-[(7,8-dihydro-8,8-dimethyl-5-(1,1-dimethylethyl)naphth-2-yl)ethynyl]benzoate (Compound 96) was converted to the title compound (white solid) using 28 mg (1.3 ml, 0.66 mmol) of LiOH (0.5M aqueous solution).