Dimethyl malate → Methyl 3,4-dihydroxybutanoate

HRID 2393871Notes

Reaction equation

[BH4-].[Li+].C[O:4][C:5](=O)[CH:6]([OH:12])[CH2:7][C:8]([O:10][CH3:11])=[O:9]>>[CH3:11][O:10][C:8](=[O:9])[CH2:7][CH:6]([OH:12])[CH2:5][OH:4]

Participants

Reactant 2

HCID 12674Dimethyl malate

HCID 4148881Lithium borohydride

Product 1

HCID 2735094Methyl 3,4-dihydroxybutanoate

Procedure

The process of claim 18 wherein about one equivalent of the lithium borohydride is reacted with the hydroxy butane dioic acid dimethyl ester to produce the 3,4-dihydroxybutyric acid -1-methyl ester.

Sources & evidence

ORD record: ord-91be732b895541fba5f20600a3d605fa
Source dataset: uspto-grants-1998_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05808107

Reaction notes

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