HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methoxyacetic Acid → Methoxyacetic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methoxyacetic Acid | HCID 12251 | — |
| Reactant | (1S,2S)-2-[2-{[3-(1H-benzimidazol-2-yl)-propyl]methylamino}ethyl]-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-ol | HCID 9830209 | — |
| Product | Methoxyacetic Acid | HCID 12251 | — |
| Product | Mibefradil | HCID 60663 | — |
Reaction Steps
The method of claim 10 further including the step of contacting the thus-formed (1S,2S)-2-[2-{[3-(1H-benzimidazol-2-yl)propyl]methylamino}ethyl]-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-ol with methoxyacetic acid or an activated derivative of methoxyacetic acid to form (1S,2S)-2-[2-{[3-(1H-benzimidazol-2-yl)propyl]methylamino}ethyl]-6-fluoro-1-isopropyl-1,2,3,4-tetrahydronaphthalen-2-yl methoxyacetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05808088 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-10b51126afd446d9b559bba74e746541 |
| Source note | uspto-grants-1998_09 |