4-Bromobenzyl bromide → HCID 18977582, compound

HRID 2393927Notes

Reaction equation

HRID 2393927 reaction equation
CC1(C)CC(=O)C=CC1.BrC1C=CC(CBr)=CC=1.[CH2:19]=[C:20]1[CH2:25][CH2:24][CH2:23][C:22]([CH3:27])([CH3:26])[CH:21]1[CH2:28][C:29]1[CH:34]=[C:33](OC)[C:32]([Br:37])=[CH:31][C:30]=1O>>[CH2:19]=[C:20]1[CH2:25][CH2:24][CH2:23][C:22]([CH3:27])([CH3:26])[CH:21]1[CH2:28][C:29]1[CH:34]=[CH:33][C:32]([Br:37])=[CH:31][CH:30]=1

Participants

4

Reactant 3

HCID 685274-Bromobenzyl bromideHCID 1383222-Cyclohexenone, 5,5-dimethyl-HCID 10593144HCID 10593144, compound

Product 1

HCID 18977582HCID 18977582, compound

Procedure

This compound was prepared from 5,5-dimethylcyclohex-2-en-1-one (8) and p-bromobenzyl bromide in three steps in the manner described for the synthesis of olefin (13). 1H NMR (400 MHz, CDCl3) δ 0.94 and 0.97 (2s, 2×3H, geminal-CH3 's), 2.62 and 2.82 (d of ABq, 2H, benzylic-CH2), 4.25 and 4.61 (2s, 2×1H, methylidene-CH2), 6.98 (d, 2H, Ar--H), 7.34 ppm (d, 2H, Ar--H). [This compound is also referred to as Compound "O" or 120130]

Sources & evidence

ORD record
ord-f8b972d3a8df422a9b2adfdba86ec417
Source dataset
uspto-grants-1998_09
Patent number
US05808139

Reaction notes

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