Hydrazine → 5'-S-(2-aminoethyl)-N(6)-(4-nitrobenzyl)-5'-thioadenosine

HRID 2394213Notes

Reaction equation

HRID 2394213 reaction equation
C1(=O)[N:5]([CH2:6][CH2:7][S:8][CH2:9][C@H:10]2[O:14][C@@H:13]([N:15]3[C:34]4[N:33]=[CH:32][N:31]=[C:19]([NH:20][CH2:21][C:22]5[CH:27]=[CH:26][C:25]([N+:28]([O-:30])=[O:29])=[CH:24][CH:23]=5)[C:18]=4[N:17]=[CH:16]3)[C@H:12]([OH:35])[C@@H:11]2[OH:36])C(=O)C2=CC=CC=C12.NN>C(O)C>[NH2:5][CH2:6][CH2:7][S:8][CH2:9][C@H:10]1[O:14][C@@H:13]([N:15]2[C:34]3[N:33]=[CH:32][N:31]=[C:19]([NH:20][CH2:21][C:22]4[CH:27]=[CH:26][C:25]([N+:28]([O-:30])=[O:29])=[CH:24][CH:23]=4)[C:18]=3[N:17]=[CH:16]2)[C@H:12]([OH:35])[C@@H:11]1[OH:36]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 14802631HCID 14802631, compound

Product 1

HCID 1642935'-S-(2-aminoethyl)-N(6)-(4-nitrobenzyl)-5'-thioadenosine

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

deprotection of the product of step (b) by heating with hydrazine in ethanol to give the phthaloyl hydrazide salt of 5'-S-(2-aminoethyl)-N6 -(4-nitrobenzyl)-5'-thioadenosine; and

Sources & evidence

ORD record
ord-1eb8777093c84bdfaf84a563c996b11c
Source dataset
uspto-grants-1998_09
Patent number
USRE035904

Reaction notes

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