Acetic Anhydride → HCID 54362870, compound

HRID 2394286Notes

Reaction equation

HRID 2394286 reaction equation
[Cl:1][C:2]1[C:7]([C:8]([CH2:10][C:11]([O:13][CH2:14][CH3:15])=[O:12])=[O:9])=[CH:6][N:5]=[C:4]([Cl:16])[C:3]=1[Cl:17].[CH:18]([O-])([O-])[O:19][CH2:20][CH3:21].C(OC(=O)C)(=O)C>>[Cl:1][C:2]1[C:7]([C:8]([C:10](=[CH:18][O:19][CH2:20][CH3:21])[C:11]([O:13][CH2:14][CH3:15])=[O:12])=[O:9])=[CH:6][N:5]=[C:4]([Cl:16])[C:3]=1[Cl:17]

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 18973127HCID 18973127, compoundHCID 53630039Ethylorthoformate

Product 1

HCID 54362870HCID 54362870, compound

Procedure

87.0 g (0.29 mol) of ethyl 2-(4,5,6-trichloronicotinoyl)acetate are heated with 56.2 g of (0.38 mol) of ethyl orthoformate and 65.2 g of acetic anhydride at 150°-160° C. for two hours. All volatile components are removed, initially in vacuo and then under a high vacuum up to 100° C.

Workup

  1. customAll volatile components are removed, initially in vacuo
  2. customup to 100° C.

Sources & evidence

ORD record
ord-80ebb7f8c51c4f918bc2ada5fbe83d0e
Source dataset
uspto-grants-1998_09
Patent number
US05811433

Reaction notes

Loading…