Water → HCID 18973177, compound

HRID 2394296Notes

Reaction equation

HRID 2394296 reaction equation
[Cl:1][C:2]1[C:13]2=[C:14]3[C:5]([C:6](=[O:21])[C:7]([C:16]([O:18]CC)=[O:17])=[CH:8][N:9]3[CH:10]([CH3:15])[CH2:11][O:12]2)=[CH:4][N:3]=1.O.S(=O)(=O)(O)O>C(O)(=O)C>[Cl:1][C:2]1[C:13]2=[C:14]3[C:5]([C:6](=[O:21])[C:7]([C:16]([OH:18])=[O:17])=[CH:8][N:9]3[CH:10]([CH3:15])[CH2:11][O:12]2)=[CH:4][N:3]=1

Participants

5

Reactant 3

HCID 962WaterHCID 1118Sulfuric AcidHCID 18973179HCID 18973179, compound

Product 1

HCID 18973177HCID 18973177, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

0.95 g (3.1 mmol) of ethyl 9-chloro-3-methyl-6-oxo-3,6-dihydro-2H-1-oxa-3a,8-diazaphenalene-5-carboxylate are heated at reflux in a mixture of 4 ml of acetic acid, 4 ml of water and 0.4 ml of concentrated sulphuric acid for four hours. The cooled mixture is put into ice-water, the product is isolated and washed with water.

Workup

  1. customthe product is isolated
  2. washwashed with water

Sources & evidence

ORD record
ord-347a81d6516f450694b865f812438069
Source dataset
uspto-grants-1998_09
Patent number
US05811433

Reaction notes

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