Acetic Acid → HCID 18972986, compound

Participants

Reaction Steps

Lithium hydroxide (80 mg 1.8 mmol) and water (2 ml) were added to a solution of the product of step (c) (280 mg, 0.6 mmol) in THF (5 ml) and the mixture was stirred at room temperature for 16 hours. Acetic acid (0.5 ml) was added and the mixture was partitioned between ethyl acetate and water. The organic layer was dried (Na2SO4) and the solvent was evaporated under reduced pressure to give the title compound as a colourless foam (234 mg) m/e (CI+) 438 (MH+).

Provenance & Evidence