HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → HCID 18973024, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | Chlorosulfonyl isocyanate | HCID 70918 | — |
| Reactant | HCID 15228322 | HCID 15228322 | — |
| Reactant | HCID 18973061 | HCID 18973061 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 18973024 | HCID 18973024 | — |
Reaction Steps
The title compound was prepared from 6-chloro-3-(2-furoyl)-4-azaoxindole (Example 12) according to the procedure of Example 2C, using 400 mg (1.5 mmol) 6-chloro-3-(2-furoyl)-4-azaoxindole, 0.19 ml (2.25 mmol) N-chlorosulfonyl isocyanate and 15 ml acetonitrile. The crude N-chlorosulfonyl carboxamide was hydrolysed by stirring in DMSO (5 ml), for 2 hours in a flask open to the air. The product was isolated by dilution with water filtration, and recrystallization from acetic acid. Yield: 160 mg (35%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05811432 |
| Source dataset | uspto-grants-1998_09 |
| ORD ID | ord-9692c5c7950f472b92c4b1f35878f491 |
| Source note | uspto-grants-1998_09 |